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When skin is exposed to UV radiation or oxidative stress, the melanocytes produce melanin, which accumulates in melanosomes, and is then transported to keratinocytes surrounding the melanocytes through dendrites to form supranuclear melanin caps to protect skin from photoaging [6]

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Vitamin B12 deficiency is common in those with epilepsy, either as a cause or as a result of treatment with anti-epileptic drugs (Youness, etal, 2020